SCHEMBL26494348

SCHEMBL26494348

COCCOCCCN(C)C(=O)OC(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.36
CA14 Q9ULX7 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
PDK2 Q15119 1/20 0.33
DDB1 Q16531 1/20 0.33
CRBN Q96SW2 1/20 0.33
CTSK P43235 2/20 0.32
TRPV4 Q9HBA0 1/20 0.31
FPR3 P25089 1/20 0.31
FPR2 P25090 1/20 0.31
GBA1 P04062 1/20 0.30
METAP2 P50579 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26494358 0.94 L3MBTL1 (0.33) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL22957198 0.90 PDK2 (0.37) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL224144 0.90 HDAC6 (0.37) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL18755717 0.86 CA14 (0.35) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL21998123 0.85 TSHR (0.38) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL31634922 0.84 L3MBTL1 (0.36) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL21997101 0.84 L3MBTL1 (0.36) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL21996785 0.84 CA14 (0.36) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL7227365 0.83 CA14 (0.40) L3MBTL1CA14HDAC1HDAC2HDAC6
SCHEMBL22276510 0.83 PDK2 (0.40) L3MBTL1CA14HDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4504694-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES Capstan Therapeutics, Inc. (US) 2025-02-12 EP disclosed
US-20240299311-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2024-09-12 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023196444-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed
WO-2023196444-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 L3MBTL1 98/4885CA14 3020/4885HDAC1 1169/4885
US-20240299311-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 L3MBTL1 98/4885CA14 3020/4885HDAC1 1169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.