SCHEMBL26495337

SCHEMBL26495337

CNCCCCCCN1CCC(O)CC1

nearest known ligand 0.65

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 6/20 0.48
PRMT6 Q96LA8 6/20 0.48
PRMT8 Q9NR22 2/20 0.48
PRMT1 Q99873 1/20 0.48
SPHK1 Q9NYA1 1/20 0.43
GNAI3 P08754 4/20 0.41
GNAO1 P09471 4/20 0.41
GNAI1 P63096 4/20 0.41
SIGMAR1 Q99720 1/20 0.39
MAOB P27338 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26494036 1.00 CARM1 (0.48) CARM1PRMT6PRMT8PRMT1SPHK1
SCHEMBL26495258 0.98 CARM1 (0.50) CARM1PRMT6PRMT8PRMT1SPHK1
SCHEMBL14272558 0.92 CARM1 (0.52) CARM1PRMT6PRMT8PRMT1SPHK1
SCHEMBL1108189 0.84 CARM1 (0.67) CARM1PRMT6PRMT8PRMT1SIGMAR1
SCHEMBL23506931 0.83 CARM1 (0.71) CARM1PRMT6PRMT8PRMT1SIGMAR1
SCHEMBL12291008 0.81 CARM1 (0.44) CARM1PRMT6PRMT8PRMT1
SCHEMBL12291015 0.81 CARM1 (0.44) CARM1PRMT6PRMT8PRMT1
SCHEMBL13822620 0.80 CARM1 (0.54) CARM1PRMT6PRMT8PRMT1GNAI3
SCHEMBL1891298 0.79 GNAO1 (0.63) SPHK1GNAI3GNAO1GNAI1
SCHEMBL19603949 0.79 GNAO1 (0.63) SPHK1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 US disclosed
WO-2023196444-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES CAPSTAN THERAPEUTICS, INC. (US) 2023-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320995-A1 IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES PLTP, LNPEP, PLIN3 CARM1 3427/4885PRMT6 3265/4885PRMT8 3449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.