Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.37 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | KDM4A | O75164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 3/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26494037 | 1.00 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26495264 | 0.98 | PRMT3 (0.39) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL3317561 | 0.93 | PRMT3 (0.42) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26494041 | 0.91 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26494039 | 0.91 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26495343 | 0.91 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26495349 | 0.91 | S1PR2 (0.41) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL14178222 | 0.91 | EPHX1 (0.48) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL25075486 | 0.89 | PRMT3 (0.39) | S1PR2S1PR1S1PR3S1PR5EPHX1 | |
| SCHEMBL26495268 | 0.89 | PRMT3 (0.39) | S1PR2S1PR1S1PR3S1PR5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| WO-2023196444-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | PLTP, LNPEP, PLIN3 | S1PR2 927/4885S1PR1 743/4885S1PR3 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.