Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL10887714 | 0.82 | THRB (0.47) | ALDH1A1HPGDKDM4EKMT2AMAPT | |
| Acrylamide SCHEMBL2650525 | 0.80 | MTNR1A (0.42) | ALDH1A1MTNR1AMTNR1BKDM4EACHE | |
| Acrylic Acid Ethyl Ester SCHEMBL11788641 | 0.80 | CYP1A2 (0.46) | ALDH1A1HPGDCDC25BCDC25ACDC25C | |
| Acrylic Acid SCHEMBL2650093 | 0.79 | KDM4E (0.48) | ALDH1A1HPGDMTNR1AMTNR1BKDM4E | |
| Alcohol SCHEMBL28080393 | 0.78 | MTNR1A (0.47) | ALDH1A1HPGDMTNR1AMTNR1BKDM4E | |
| SCHEMBL2690695 | 0.78 | HDAC8 (0.55) | ALDH1A1HPGDMTNR1AMTNR1BKDM4E | |
| SCHEMBL2690696 | 0.78 | HDAC8 (0.55) | ALDH1A1HPGDMTNR1AMTNR1BKDM4E | |
| Acrylic Acid Ethyl Ester SCHEMBL10935236 | 0.78 | THRB (0.47) | ALDH1A1HPGDKDM4EKMT2AMAPT | |
| SCHEMBL2650526 | 0.78 | TSHR (0.44) | ALDH1A1MTNR1AMTNR1BKDM4EKMT2A | |
| Acrylic Acid Ethyl Ester SCHEMBL19460923 | 0.77 | KMT2A (0.51) | ALDH1A1HPGDCDC25BCDC25ACDC25C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |