SCHEMBL2649680

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15075603	0.89	MAPK11 (1.00)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL19868925	0.89	MAPK11 (1.00)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL9201704	0.87	MAPK13 (0.79)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL4553281	0.87	ALOX5 (1.00)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL6465062	0.87	ALOX5 (1.00)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL19869017	0.87	MAPK14 (0.69)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL15987046	0.86	ALOX5 (0.74)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL19857273	0.86	MAPK11 (0.73)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL4552013	0.86	ALOX5 (1.00)	MAPK11MAPK14MAPK13GCGRMAPK12
	SCHEMBL27934587	0.86	MAPK11 (0.73)	MAPK11MAPK14MAPK13GCGRMAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.