Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342120 | 0.96 | SERPINE1 (0.41) | GRIK1KDM4ERAB9ANPC1SERPINE1 | |
| SCHEMBL1340657 | 0.93 | ALDH1A1 (0.40) | KDM4ERAB9ANPC1DHODHHSD17B10 | |
| SCHEMBL2649833 | 0.92 | ALDH1A1 (0.40) | GRIK1KDM4ERAB9ANPC1CNR1 | |
| SCHEMBL10002704 | 0.88 | GRIK1 (0.37) | GRIK1KDM4ERAB9ANPC1DHODH | |
| SCHEMBL1341032 | 0.87 | LMNA (0.42) | GRIK1RAB9ANPC1NR1H4LMNA | |
| SCHEMBL1341838 | 0.87 | SERPINE1 (0.39) | GRIK1KDM4ERAB9ANPC1SERPINE1 | |
| SCHEMBL1341115 | 0.87 | KMT2A (0.41) | KDM4ERAB9ANPC1DHODHALDH1A1 | |
| SCHEMBL1342268 | 0.84 | CSNK1D (0.39) | GRIK1LMNAMAPTKMT2A | |
| SCHEMBL1341804 | 0.84 | SERPINE1 (0.38) | GRIK1KDM4ERAB9ANPC1SERPINE1 | |
| SCHEMBL1340913 | 0.84 | MAPT (0.44) | KDM4ERAB9ANPC1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |