Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649828 | 0.92 | GRIK1 (0.41) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL10002707 | 0.89 | ALDH1A1 (0.38) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL1342120 | 0.88 | SERPINE1 (0.41) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL1340657 | 0.84 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDNPSR1HSD17B10 | |
| SCHEMBL10002704 | 0.81 | GRIK1 (0.37) | ALDH1A1KDM4ECNR1CNR2MEN1 | |
| SCHEMBL2650087 | 0.81 | MAPT (0.38) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL1341838 | 0.80 | SERPINE1 (0.39) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL1341338 | 0.79 | GCK (0.39) | ALDH1A1CASP3SENP8SENP7SENP6 | |
| SCHEMBL1341158 | 0.79 | MAPT (0.39) | CASP3SENP8SENP7SENP6CNR1 | |
| SCHEMBL1341032 | 0.78 | LMNA (0.42) | MEN1KMT2ARAB9AGRIK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |