Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343424 | 0.95 | GHSR (0.38) | GHSRCHRNA4SLC6A3MAPTALDH1A1 | |
| SCHEMBL1340210 | 0.91 | GAA (0.35) | MAPTRAB9ASMN1; SMN2ALDH1A1ITK | |
| SCHEMBL2649830 | 0.89 | CHRNA4 (0.32) | GHSRCHRNA4SLC6A3MAPTHTT | |
| SCHEMBL1342788 | 0.82 | MAPT (0.33) | MAPTHTTRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1342409 | 0.82 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL1341777 | 0.82 | ALDH1A1 (0.40) | GHSRCHRNA4SLC6A3MAPTHTT | |
| SCHEMBL1342835 | 0.81 | GAA (0.36) | MAPTRAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL1342842 | 0.81 | GHSR (0.38) | GHSRCHRNA4SLC6A3MAPTRAB9A | |
| SCHEMBL1341285 | 0.80 | IDH1 (0.37) | GHSRCHRNA4SLC6A3MAPTALDH1A1 | |
| SCHEMBL1340896 | 0.80 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |