Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227127 | 0.83 | MAPT (0.79) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL4345200 | 0.83 | NPC1 (1.00) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL30679624 | 0.81 | MAPT (0.79) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29227142 | 0.81 | NPC1 (0.79) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29227155 | 0.81 | MAPT (0.79) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2664435 | 0.80 | GCGR (0.54) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31573995 | 0.80 | MAPT (0.73) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10902286 | 0.78 | NPC1 (0.79) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5663499 | 0.78 | NPC1 (0.73) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL15414421 | 0.76 | NPC1 (0.62) | RAB9ANPC1MAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |