Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.79 |
| ▸ | RAB9A | P51151 | 6/20 | 0.79 |
| ▸ | MAPT | P10636 | 6/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345200 | 0.88 | NPC1 (1.00) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL30679624 | 0.86 | MAPT (0.79) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29227127 | 0.86 | MAPT (0.79) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL29227155 | 0.86 | MAPT (0.79) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31574004 | 0.85 | RAB9A (0.69) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL10902286 | 0.83 | NPC1 (0.79) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31573995 | 0.83 | MAPT (0.73) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL5663499 | 0.83 | NPC1 (0.73) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2649925 | 0.81 | RAB9A (0.70) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL31573994 | 0.80 | RAB9A (0.73) | NPC1RAB9AMAPTL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |