Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4467822 | 0.82 | PLK1 (0.44) | PLK1CA2CA1CA9MEN1 | |
| SCHEMBL6851155 | 0.81 | MEN1 (0.38) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL247360 | 0.77 | CNR2 (0.55) | MEN1KMT2ACDC25BGAAMAPT | |
| SCHEMBL9470141 | 0.76 | GPR3 (0.37) | CA2CA1CA9MEN1KMT2A | |
| SCHEMBL14400507 | 0.76 | SLC2A1 (0.42) | MEN1KMT2AGAACYP2C9SLC2A1 | |
| SCHEMBL466508 | 0.75 | MAPT (0.52) | PLK1CA2CTSDCA1CA9 | |
| SCHEMBL5891933 | 0.75 | PLK1 (0.73) | PLK1CTSDKMT2AALDH1A1KDM4E | |
| SCHEMBL203899 | 0.74 | MEN1 (0.42) | MEN1KMT2AGAA | |
| SCHEMBL29706003 | 0.74 | MEN1 (0.42) | MEN1KMT2AGAA | |
| SCHEMBL8636736 | 0.73 | IDO1 (0.46) | PLK1ALDH1A1HPGDSCDC25BCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |