Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957209 | 1.00 | NR4A1 (0.48) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL7537971 | 0.88 | NR4A1 (0.53) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL28798 | 0.82 | NR4A1 (0.65) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL29406630 | 0.82 | NR4A1 (0.65) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL30838413 | 0.82 | NR4A1 (0.65) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL30838412 | 0.82 | NR4A1 (0.65) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL23528851 | 0.82 | ALDH1A1 (0.39) | ALDH1A1ALOX15KDM4ETSHRTHRB | |
| SCHEMBL7195362 | 0.82 | NR4A1 (0.47) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL31518427 | 0.82 | NR4A1 (0.47) | NR4A1NR4A2NR4A3WDR5ALDH1A1 | |
| SCHEMBL1506782 | 0.82 | NR4A1 (0.47) | NR4A1NR4A2NR4A3WDR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852045-A | Preparation method of rana medicine | 河北圣雪大成制药有限责任公司 | 2024-10-29 | — | — | CN | claimed |
| CN-114456059-B | Method for preparing aforana intermediate | 丽珠集团新北江制药股份有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-114113388-B | Method for detecting related substances in 4-oxime methyl-1-naphthoic acid | 丽珠集团新北江制药股份有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-114456059-A | Method for preparing Aforana intermediate | 丽珠集团新北江制药股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114113388-A | Method for detecting related substances in 4-oximinomethyl-1-naphthoic acid | 丽珠集团新北江制药股份有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-112679338-A | Method for preparing oxazoline insecticide alfilana intermediate | 丽珠集团新北江制药股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2026-03-12 | — | — | US | disclosed |
| US-12497370-B2 | Isoxazoline derivatives | ELANCO TIERGESUNDHEIT AG (CH) | 2025-12-16 | — | — | US | disclosed |
| CN-120004816-A | Isoxazoline derivatives | 礼蓝动物保健有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-115210221-B | Isoxazoline derivatives as pesticides | 礼蓝动物保健有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-118852045-A | Preparation method of rana medicine | 河北圣雪大成制药有限责任公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118852045-A | Preparation method of rana medicine | 河北圣雪大成制药有限责任公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-118146085-A | Treatment method for material ending in middle of reaction for preparing 1, 4-naphthalene dicarboxylic acid by oxidizing 1-methyl-4-naphthalene carboxylic acid by oxygen | 黄石市利福达医药化工有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-2002005646-A2 | COMPOSITIONS FOR REPELLING CRAWLING INSECTS | S.C. JOHNSON & SON, INC. (US) (US) | 2002-01-24 | — | — | WO | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| US-4016195-A | OPTICAL BRIGHTENERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4000275-A | BENZIMIDAZO(2,1-B) QUINAZOLIN-12(6H)ONES | ELI LILLY AND COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3957846-A | OPTICAL BRIGHTENERS, LACQUERS, SYNTHETIC FIBERS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497370-B2 | Isoxazoline derivatives | CYP3A7, CYP4X1, CYP2A7 | NR4A1 1679/4885NR4A2 1867/4885NR4A3 1908/4885 |
| US-20260070879-A1 | ISOXAZOLINE DERIVATIVES | CHRM1, CBR3, AFF1 | NR4A1 287/4885NR4A2 827/4885NR4A3 643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.