SCHEMBL26501138

SCHEMBL26501138

CC(C)=CCC/C(C)=C/CC/C(C)=C/C(=O)Oc1ccccc1C=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 0.43
POLB P06746 2/20 0.43
MAPT P10636 2/20 0.43
ICMT O60725 1/20 0.43
GMNN O75496 1/20 0.43
TRPA1 O75762 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
TSHR P16473 1/20 0.43
NFKB1 P19838 1/20 0.43
CDK2 P24941 1/20 0.43
RECQL P46063 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
HSD17B10 Q99714 1/20 0.43
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
ACHE P22303 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26500837 0.97 KDM4E (0.44) TRPV1POLBMAPTICMTGMNN
SCHEMBL26500803 0.84 KDM4E (0.46) TRPV1POLBMAPTKDM4EATM
SCHEMBL26500818 0.83 GLA (0.43) TRPV1POLBMAPTICMTGMNN
SCHEMBL26500808 0.83 TRPV1 (0.48) TRPV1POLBKDM4EATMACHE
SCHEMBL11575323 0.82 KDM4E (0.51) TRPV1POLBMAPTICMTGMNN
SCHEMBL26500809 0.82 KDM4E (0.44) TRPV1POLBMAPTICMTGMNN
SCHEMBL26500812 0.82 TRPV1 (0.45) TRPV1POLBKDM4EATMACHE
SCHEMBL26501141 0.81 SLC6A3 (0.46) TRPV1POLBMAPTICMTGMNN
SCHEMBL26501152 0.81 ACHE (0.43) TRPV1POLBMAPTICMTGMNN
SCHEMBL31618356 0.80 ALOX15 (0.55) TRPV1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023072285-A1 ENOATE COMPOUND CONTAINING AROMATIC RING, AND PREPARATION THEREFOR AND USE THEREOF 中国农业大学 2023-05-04 WO disclosed