Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24920712 | 0.83 | NPSR1 (0.34) | PDE4BCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26502000 | 0.81 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL317021 | 0.75 | — | — | |
| SCHEMBL457302 | 0.75 | — | — | |
| SCHEMBL31314878 | 0.75 | CYP2D6 (0.41) | — | |
| SCHEMBL3396955 | 0.75 | NCF1 (0.35) | — | |
| SCHEMBL31314866 | 0.75 | CYP2D6 (0.41) | — | |
| SCHEMBL13783474 | 0.75 | BCHE (0.33) | — | |
| SCHEMBL5944019 | 0.75 | CYP2D6 (0.41) | — | |
| SCHEMBL2628598 | 0.74 | BCHE (0.38) | CHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070605-A1 | METHODS OF PREPARING 6-MEMBERED AZA-HETEROCYCLIC CONTAINING DELTA-OPIOID RECEPTOR MODULATING COMPOUNDS | TREVENA, INC. (US) | 2023-05-04 | — | — | WO | disclosed |