Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | FABP3 | P05413 | 1/20 | 0.56 |
| ▸ | FABP4 | P15090 | 1/20 | 0.56 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL380091 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| Hydrochloric Acid SCHEMBL5883332 | 0.98 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| Bromomethane SCHEMBL5883760 | 0.94 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL5106705 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL5100118 | 0.88 | MAPT (0.60) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL18415557 | 0.87 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL34420050 | 0.87 | CA12 (0.64) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL3910619 | 0.87 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL4654120 | 0.87 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2ACYP2C9HPGD | |
| SCHEMBL5099460 | 0.87 | TDP1 (0.57) | ALDH1A1MEN1KMT2ACYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 274 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649209-B2 | Crystalline freebase forms of a biphenyl compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2023-05-16 | — | — | US | claimed |
| CN-115850157-A | Preparation method of 1-benzylpiperidine-4-yl [1,1' -biphenyl ] -2-yl carbamate | 济南大学 | 2023-03-28 | — | — | CN | claimed |
| US-20220306580-A1 | CRYSTALLINE FREEBASE FORMS OF A BIPHENYL COMPOUND | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2022-09-29 | — | — | US | claimed |
| US-11008289-B2 | Crystalline freebase forms of a biphenyl compound | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2021-05-18 | — | — | US | claimed |
| EP-3029026-B1 | NOVEL BIPHENYL DERIVATIVE AND METHOD FOR PREPARING SAME | DONG A ST CO LTD (KR) | 2018-12-05 | — | — | EP | claimed |
| EP-2991975-B1 | INHIBITORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE, COMPOSITIONS, PRODUCTS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE AMEDEO AVOGADRO (IT) | 2017-07-19 | — | — | EP | claimed |
| EP-2621917-A1 | CRYSTALLINE OXALATE SALTS OF A DIAMIDE COMPOUND | Theravance, Inc. (US) | 2013-08-07 | — | — | EP | claimed |
| WO-2012044825-A1 | CRYSTALLINE OXALATE SALTS OF A DIAMIDE COMPOUND | THERAVANCE, INC. (US) | 2012-04-05 | — | — | WO | claimed |
| EP-2409977-A1 | AMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-25 | — | — | EP | claimed |
| EP-0713877-A1 | QINGHAOSU DERIVATIVES AGAINST AIDS | LUO, Xuande (CN) | 1996-05-29 | — | — | EP | claimed |
| EP-0027330-B1 | PROCESS FOR THE PRODUCTION OF METHYLENEDICARBANILATES AND THE COMPOUNDS THUS OBTAINED | MITSUBISHI KASEI CORPORATION (JP) | 1984-12-12 | — | — | EP | claimed |
| US-4476317-A | HETEROPOLYMOLYBDIC ACID OR HETEROPOLYTUNGSTIC ACID | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1984-10-09 | — | — | US | claimed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | claimed |
| US-20250179019-A1 | CRYSTALLINE FREEBASE FORMS OF A BIPHENYL COMPOUND | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2025-06-05 | — | — | US | disclosed |
| US-12258316-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2025-03-25 | — | — | US | disclosed |
| CN-119178828-A | Method for detecting related substances of raffinacine | 平光制药股份有限公司 | 2024-12-24 | — | — | CN | disclosed |
| EP-0014103-B1 | IMPROVED PROCESS FOR THE MANUFACTURE OF CARBAMATES | THE HALCON SD GROUP, INC. (US) | 1983-05-11 | — | — | EP | disclosed |
| EP-0027330-A1 | Process for the production of methylenedicarbanilates and the compounds thus obtained | MITSUBISHI KASEI CORPORATION (JP) | 1981-04-22 | — | — | EP | disclosed |
| US-4258201-A | CATALYTIC CARBONYLATION OF PRIMARY OR SECONDARY AMINES WITH CARBON MONOXIDE AND ALCOHOLS | HALCON RESEARCH AND DEVELOPMENT CORP. (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0014103-A2 | Improved process for the manufacture of carbamates | THE HALCON SD GROUP, INC. (US) | 1980-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649209-B2 | Crystalline freebase forms of a biphenyl compound | TBCB, FFAR1, CRYAB | ALDH1A1 2304/4885MEN1 1790/4885KMT2A 1028/4885 |
| US-11008289-B2 | Crystalline freebase forms of a biphenyl compound | TBCB, FFAR1, CRYAB | ALDH1A1 2304/4885MEN1 1790/4885KMT2A 1028/4885 |
| US-12258316-B2 | Biphenyl compounds useful as muscarinic receptor antagonists | CHRM2, CHRM1, CHRM3 | ALDH1A1 1082/4885MEN1 747/4885KMT2A 2049/4885 |
| US-20220306580-A1 | CRYSTALLINE FREEBASE FORMS OF A BIPHENYL COMPOUND | TBCB, FFAR1, CRYAB | ALDH1A1 2304/4885MEN1 1790/4885KMT2A 1028/4885 |
| US-20250179019-A1 | CRYSTALLINE FREEBASE FORMS OF A BIPHENYL COMPOUND | TBCB, FFAR1, CRYAB | ALDH1A1 2304/4885MEN1 1790/4885KMT2A 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.