Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26501780 | 0.87 | USP5 (0.47) | RAB9ANPC1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL26501785 | 0.85 | RAB9A (0.36) | RAB9ANPC1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL26501795 | 0.83 | RAB9A (0.35) | RAB9ANPC1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL26501789 | 0.82 | TAAR1 (0.37) | RAB9ANPC1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL26501671 | 0.81 | CNR2 (0.33) | L3MBTL1LMNAHTTPTGDR2 | |
| SCHEMBL26501696 | 0.79 | SMN1; SMN2 (0.39) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL26501783 | 0.78 | NPC1 (0.51) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL7707768 | 0.73 | GABRR1 (0.40) | SMN1; SMN2L3MBTL1POLBMAPTLMNA | |
| SCHEMBL26501796 | 0.73 | HDAC1 (0.35) | RAB9ANPC1SMN1; SMN2KDM4EGSK3B | |
| SCHEMBL26501652 | 0.72 | DHFR (0.34) | L3MBTL1LMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230321092-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | HMGCR, GCDH, CYP11A1 | RAB9A 3971/4885NPC1 189/4885SMN1; SMN2 1609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.