Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 7/20 | 0.42 |
| ▸ | CA2 | P00918 | 7/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26075285 | 0.89 | CA1 (0.51) | CA1CA2CA9CA12CA7 | |
| SCHEMBL26075166 | 0.86 | CA1 (0.44) | CA1CA2CA9CA12CA7 | |
| SCHEMBL26075366 | 0.80 | CA1 (0.50) | CA1CA2CA12CA7CA13 | |
| SCHEMBL26075284 | 0.79 | ALDH1A1 (0.44) | CA1CA2CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL26075094 | 0.78 | CA1 (0.39) | CA1CA2CA9CA12CA7 | |
| SCHEMBL14324823 | 0.74 | ALOX5AP (0.41) | CA1CA2CA9CA12CA7 | |
| SCHEMBL25359552 | 0.73 | CA2 (0.38) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL20237716 | 0.71 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29505942 | 0.71 | CA1 (0.48) | CA1CA2CA9CA12CA7 | |
| SCHEMBL15453138 | 0.69 | CA1 (0.49) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |