Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.42 |
| ▸ | ABAT | P80404 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649949 | 0.91 | ALDH1A1 (0.64) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL2650454 | 0.89 | ALDH1A1 (0.48) | FDPSALDH1A1MAPK1TSHRMAPT | |
| SCHEMBL6739941 | 0.86 | FDPS (0.54) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL8615157 | 0.86 | FDPS (0.54) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL7466433 | 0.84 | FDPS (0.53) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL7467304 | 0.84 | FDPS (0.57) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL2649856 | 0.83 | MGAM (0.45) | FDPSALDH1A1MAPK1TSHRMAPT | |
| SCHEMBL7462928 | 0.83 | FDPS (0.51) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL2744232 | 0.83 | TUBB1 (0.54) | FDPSALDH1A1MAPK1TSHRTNFRSF1A | |
| SCHEMBL10572490 | 0.83 | FDPS (0.51) | FDPSALDH1A1MAPK1TSHRTNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |