Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Syringaldehyde SCHEMBL9370844 | 0.94 | TUBB1 (0.49) | TUBB1FDPSALDH1A1MAPK1TRIM24 | |
| SCHEMBL7122419 | 0.91 | TUBB1 (0.49) | TUBB1FDPSALDH1A1MAPK1TRIM24 | |
| SCHEMBL13168474 | 0.91 | FDPS (0.50) | TUBB1FDPSALDH1A1MAPK1TRIM24 | |
| SCHEMBL19737048 | 0.90 | TUBB1 (0.50) | TUBB1FDPSALDH1A1MAPK1TRIM24 | |
| SCHEMBL15771884 | 0.89 | ALDH1A1 (0.51) | TUBB1FDPSALDH1A1MAPK1HPGD | |
| SCHEMBL9153088 | 0.89 | ALDH1A1 (0.67) | TUBB1FDPSALDH1A1MAPK1HPGD | |
| SCHEMBL14723251 | 0.89 | TUBB1 (0.49) | TUBB1FDPSALDH1A1MAPK1TRIM24 | |
| SCHEMBL8615157 | 0.86 | FDPS (0.54) | FDPSALDH1A1MAPK1TRIM24HPGD | |
| SCHEMBL6739941 | 0.86 | FDPS (0.54) | FDPSALDH1A1MAPK1TRIM24HPGD | |
| SCHEMBL7466433 | 0.84 | FDPS (0.53) | TUBB1FDPSALDH1A1MAPK1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110002972-B | Method for depolymerizing lignin into aromatic compounds through photocatalysis | 吉林大学 | 2021-07-27 | — | — | CN | disclosed |
| US-8883931-B2 | Polynitrones and use thereof for cross-linking unsaturated polymers | HEINRICH-HEINE-UNIVERSITAT (DE) | 2014-11-11 | — | — | US | disclosed |
| US-8883931-B2 | Polynitrones and use thereof for cross-linking unsaturated polymers | HEINRICH-HEINE-UNIVERSITAT (DE) | 2014-11-11 | — | — | US | disclosed |
| US-8883931-B2 | Polynitrones and use thereof for cross-linking unsaturated polymers | HEINRICH-HEINE-UNIVERSITAT (DE) | 2014-11-11 | — | — | US | disclosed |
| US-8178727-B2 | Bis(arylmethylidene)acetone compound, anti-cancer agent, carcinogenesis-preventive agent, inhibitor of expression of Ki-Ras, ErbB2, c-Myc and Cycline D1, β-catenin-degrading agent, and p53 expression enhancer | NATIONAL UNIVERSITY CORPORATION TOHOKU UNIVERSITY (JP) | 2012-05-15 | — | — | US | disclosed |
| US-20100273910-A1 | POLYNITRONES AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | HEINRICH-HEINE-UNIVERSITÄT (DE) | 2010-10-28 | — | — | US | disclosed |
| US-20100273910-A1 | POLYNITRONES AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | HEINRICH-HEINE-UNIVERSITÄT (DE) | 2010-10-28 | — | — | US | disclosed |
| US-20100273910-A1 | POLYNITRONES AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | HEINRICH-HEINE-UNIVERSITÄT (DE) | 2010-10-28 | — | — | US | disclosed |
| EP-2225321-A1 | POLYNITRONS, AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | Heinrich-Heine-Universität (DE) | 2010-09-08 | — | — | EP | disclosed |
| US-20100152493-A1 | BIS(ARYLMETHYLIDENE)ACETONE COMPOUND, ANTI-CANCER AGENT, CARCINOGENESIS-PREVENTIVE AGENT, INHIBITOR OF EXPRESSION OF Ki-Ras, ErbB2, c-Myc AND CYCLINE D1, BETA-CATENIN-DEGRADING AGENT, AND p53 EXPRESSION ENHANCER | SHIBATA, HIROYUKI (JP) | 2010-06-17 | — | — | US | disclosed |
| WO-2009074310-A1 | POLYNITRONS, AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | HEINRICH-HEINE-UNIVERSITÄT (DE) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009074310-A1 | POLYNITRONS, AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | HEINRICH-HEINE-UNIVERSITÄT (DE) | 2009-06-18 | — | — | WO | disclosed |
| US-5639782-A | ANTIINFLAMMATORY AGENT; ANTIALLERGENS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0574510-A4 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | INNOVATIVE TECH CENTER (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0574510-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992015294-A1 | NEOLIGNAN DERIVATIVES AS PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS AND 5-LIPOXYGENASE INHIBITORS | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1992-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152493-A1 | BIS(ARYLMETHYLIDENE)ACETONE COMPOUND, ANTI-CANCER AGENT, CARCINOGENESIS-PREVENTIVE AGENT, INHIBITOR OF EXPRESSION OF Ki-Ras, ErbB2, c-Myc AND CYCLINE D1, BETA-CATENIN-DEGRADING AGENT, AND p53 EXPRESSION ENHANCER | MYC, CCNE2, CCNE1 | TUBB1 723/4885FDPS 3613/4885ALDH1A1 614/4885 |
| US-20100273910-A1 | POLYNITRONES AND USE THEREOF FOR CROSS-LINKING UNSATURATED POLYMERS | PNN, MNAT1, NCL | TUBB1 1800/4885FDPS 954/4885ALDH1A1 859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.