Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650310 | 0.82 | TSHR (0.45) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL363983 | 0.81 | TSHR (0.48) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL28008252 | 0.80 | NLRP3 (0.50) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL3728016 | 0.79 | TSHR (0.43) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL10858287 | 0.78 | TSHR (0.53) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL28008699 | 0.78 | TSHR (0.46) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL31074064 | 0.78 | TSHR (0.53) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL5843818 | 0.78 | LMNA (0.44) | ALDH1A1TSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL16673225 | 0.77 | TDP1 (0.51) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 | |
| SCHEMBL10708969 | 0.77 | CASP1 (0.57) | ALDH1A1TSHRLMNASMN1; SMN2PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666659-B2 | Process for producing optically active 3-hydroxypropionic ester derivative | KANEKA CORPORATION (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20100016627-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | KANEKA CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| US-20060166342-A1 | Process for producing optically active 3-hydroxypropionic ester derivative | KANEKA CORPORATION (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1568679-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | KANEKA CORPORATION (JP) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016627-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-HYDROXYPROPIONIC ESTER DERIVATIVE | HPD, GRHPR, PAH | ALDH1A1 146/4885TSHR 2517/4885LMNA 3056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.