Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097610 | 0.79 | MMP1 (0.38) | MMP1MMP9MMP14MEN1FAAH | |
| SCHEMBL21895892 | 0.79 | MMP1 (0.40) | MMP1MMP9MMP14MEN1FAAH | |
| SCHEMBL11483 | 0.78 | MEN1 (0.55) | CYP1A2CYP2D6CYP3A4CNR1MEN1 | |
| SCHEMBL3084079 | 0.75 | — | — | |
| SCHEMBL17919955 | 0.75 | MMP1 (0.39) | MMP1MMP9MMP14 | |
| SCHEMBL21781969 | 0.74 | MEN1 (0.40) | MMP1MMP9MMP14MEN1FAAH | |
| SCHEMBL23799289 | 0.74 | FAAH (0.48) | MEN1FAAHMAPK1KMT2ACNR2 | |
| SCHEMBL20382897 | 0.73 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP3A4CNR1MMP9 | |
| SCHEMBL27173926 | 0.73 | FAAH (0.50) | CYP1A2CYP2D6CYP3A4CNR1MEN1 | |
| SCHEMBL27173927 | 0.73 | FAAH (0.50) | CYP1A2CYP2D6CYP3A4CNR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257154-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | Medilink Therapeutics (Suzhou) Co., Ltd. (CN) | 2023-10-11 | — | — | EP | disclosed |