Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 2/20 | 0.56 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.56 |
| ▸ | CSF1R | P07333 | 5/20 | 0.55 |
| ▸ | LCK | P06239 | 4/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ULK1 | O75385 | 3/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26506563 | 0.93 | ULK1 (0.53) | IGF1RPKMYT1CSF1RLCKSTAT6 | |
| SCHEMBL26506537 | 0.91 | CDK4 (0.60) | LCKEGFRULK1PRKAA2PRKAA1 | |
| SCHEMBL26506594 | 0.90 | LCK (0.56) | PKMYT1LCKSTAT6ULK1PRKAA2 | |
| SCHEMBL26506589 | 0.83 | ULK1 (0.59) | EGFRULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL26506579 | 0.83 | ULK1 (0.59) | EGFRULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL26506551 | 0.83 | ULK1 (0.61) | EGFRULK1PRKAA2PRKAA1ULK2 | |
| SCHEMBL26506580 | 0.83 | ULK1 (0.58) | IGF1REGFRULK1PRKAA2PRKAA1 | |
| SCHEMBL26506558 | 0.81 | ULK1 (0.56) | IGF1REGFRULK1PRKAA2PRKAA1 | |
| SCHEMBL26506586 | 0.81 | ULK1 (0.56) | IGF1REGFRULK1PRKAA2PRKAA1 | |
| SCHEMBL26506581 | 0.81 | ULK1 (0.56) | EGFRULK1PRKAA2PRKAA1ULK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | ULK2, ULK1, ULK3 | IGF1R 2282/4885PKMYT1 2225/4885CSF1R 3765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.