SCHEMBL265084

SCHEMBL265084

Cc1cc(C(=O)O)cc([N+](=O)[O-])c1

nearest known ligand 0.63

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.63
TPMT P51580 1/20 0.59
TP53 P04637 1/20 0.55
HCAR1 Q9BXC0 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP3A4 P08684 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
SRD5A2 P31213 1/20 0.47
ACHE P22303 1/20 0.46
ALOX5 P09917 2/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27399292 0.86 CYP3A4 (0.61) TSHRTP53TDP1CYP3A4SMN1; SMN2
SCHEMBL132541 0.86 CYP3A4 (0.65) TP53TDP1CYP3A4SMN1; SMN2MEN1
SCHEMBL232779 0.86 TP53 (0.64) TSHRTP53TDP1CYP3A4SMN1; SMN2
SCHEMBL29944162 0.86 CYP3A4 (0.65) TP53TDP1CYP3A4SMN1; SMN2MEN1
SCHEMBL10050753 0.85 TSHR (0.63) TSHRCYP3A4SMN1; SMN2MEN1KMT2A
Acetone SCHEMBL28637824 0.84 TP53 (0.58) TSHRTP53TDP1CYP3A4SMN1; SMN2
Hydrochloric Acid SCHEMBL3088495 0.84 TP53 (0.62) TSHRTP53TDP1CYP3A4SMN1; SMN2
Hydrochloric Acid SCHEMBL2299193 0.84 TP53 (0.62) TSHRTP53TDP1CYP3A4SMN1; SMN2
SCHEMBL28837773 0.84 CYP3A4 (0.63) TP53TDP1CYP3A4SMN1; SMN2MEN1
SCHEMBL9133420 0.84 TP53 (0.62) TSHRTP53TDP1CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192230-A Method for treating nitrobenzoic acid mixture as byproduct of 3-methyl-2-nitrobenzoic acid 南昌大学 2025-06-24 CN claimed
CN-112618662-A Traditional Chinese medicine formula for treating leg cramp 栾如震 2021-04-09 CN claimed
CN-120192230-A Method for treating nitrobenzoic acid mixture as byproduct of 3-methyl-2-nitrobenzoic acid 南昌大学 2025-06-24 CN disclosed
CN-115066428-B Boric acid derivatives 首药控股(北京)股份有限公司 2025-06-13 CN disclosed
US-20240027902-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-01-25 US disclosed
CN-112441907-B Method for co-producing mono-substituted methylbenzoic acid and mono-substituted phthalic acid 山东友道化学有限公司 2023-10-31 CN disclosed
US-20230305393-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-20230305394-A1 RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-11622970-B2 BCL-2 inhibitors and their use as pharmaceuticals Prelude Therapeutics Incorporation (US) 2023-04-11 US disclosed
US-11530193-B2 Kinase inhibitors THE UNIVERSITY OF MANCHESTER (GB) 2022-12-20 US disclosed
CN-115066428-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-09-16 CN disclosed
WO-1993015078-A1 CARBAPENEMS CONTAINING A CARBOXY SUBSTITUTED PHENYL GROUP, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES AND USE AS ANTIBIOTICS ZENECA LIMITED (GB) 1993-08-05 WO disclosed
EP-0135901-B1 HEAT-SENSITIVE REGISTRATION MATERIAL JUJO PAPER CO., LTD. (JP) 1988-11-30 EP disclosed
US-4705861-A AZO DYE CHEMICAL INTERMEDIATES BAYER AKTIENGESELLSCHAFT (DE) 1987-11-10 US disclosed
EP-0187231-A2 Amino phenyl benzothiazoles BAYER AG (DE) 1986-07-16 EP disclosed
US-4591888-A IMPROVED STABILITY AGAINST CONTAMINATION WITH OILY SUBSTANCES JUJO PAPER CO., LTD. (JP) 1986-05-27 US disclosed
EP-0135901-A2 Heat-sensitive registration material JUJO PAPER CO., LTD. (JP) 1985-04-03 EP disclosed
EP-0001246-B1 PREPARATION OF 2-(3'- OR 4'-AMINOPHENYL)-5(OR 6)-AMINOBENZIMIDAZOLES CASSELLA Aktiengesellschaft (DE) 1981-02-25 EP disclosed
US-4192947-A REACTING DIAMINO NITROBENZENE WITH NITROBENZOYL CHLORIDE, CYCLIZING ANILIDE IN AQUEOUS ALKALI, REDUCING NITRO GROUPS WITH SULFIDE CASSELLA AKTIENGESELLSCHAFT (DE) 1980-03-11 US disclosed
EP-0001246-A1 Preparation of 2-(3'- or 4'-aminophenyl)-5(or 6)-aminobenzimidazoles CASSELLA Aktiengesellschaft (DE) 1979-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11622970-B2 BCL-2 inhibitors and their use as pharmaceuticals BCL2, BCL2L2, BCL2L1 TSHR 3869/4885TPMT 1162/4885TP53 32/4885
US-11530193-B2 Kinase inhibitors CAMKK2, CAMK1, CAMKK1 TSHR 3310/4885TPMT 1519/4885TP53 812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.