Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340119 | 0.96 | RAB9A (0.33) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1343094 | 0.96 | MAPT (0.34) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL2651114 | 0.89 | — | — | |
| SCHEMBL1342466 | 0.89 | ALDH1A1 (0.33) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1341304 | 0.88 | MAPT (0.33) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1343081 | 0.88 | NTRK1 (0.33) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1341031 | 0.86 | MAPT (0.36) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1341958 | 0.86 | MAPT (0.35) | RAB9ALMNAMEN1MAPTHTT | |
| SCHEMBL1342169 | 0.85 | CCNE1 (0.31) | MEN1MAPTKMT2ATP53 | |
| SCHEMBL1343173 | 0.85 | LMNA (0.35) | RAB9ALMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |