SCHEMBL26512430

SCHEMBL26512430

N=C1NN=C(N)/C1=N/Nc1ccccc1Br

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
ADRA1B P35368 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL924008 0.77 L3MBTL1 (0.38) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL923224 0.60 RXFP1 (0.41)
SCHEMBL20283447 0.59 L3MBTL1 (0.42) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL16743511 0.59 RAB9A (0.62) L3MBTL1
SCHEMBL25291704 0.57 RAB9A (0.36)
SCHEMBL922338 0.57 MAPT (0.41) TSHR
SCHEMBL5670365 0.57 L3MBTL1 (0.32) L3MBTL1
SCHEMBL7351 0.56
SCHEMBL29573356 0.56
SCHEMBL922339 0.56 KDM4E (0.42) L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES UNIV COPENHAGEN (DK) 2023-10-12 US disclosed
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES UNIV COPENHAGEN (DK) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321043-A1 COMPOUNDS HAVING PSEUDOMONAS ANTI-BIOFILM PROPERTIES GMPS, PDE11A, CGAS ADRA2A 4209/4885ADRA2C 3989/4885ADRA1D 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.