Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27325123 | 0.76 | KMT2A (0.42) | L3MBTL1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL3755930 | 0.72 | — | — | |
| SCHEMBL23848857 | 0.71 | POLB (0.43) | L3MBTL1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL18137930 | 0.71 | MAPT (0.48) | HTTKMT2AMEN1NPC1LMNA | |
| SCHEMBL14304537 | 0.71 | GAA (0.46) | L3MBTL1HTTKMT2AMEN1NPC1 | |
| SCHEMBL25078194 | 0.71 | RAB9A (0.45) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1096366 | 0.71 | MAPT (0.48) | HTTKMT2AMEN1NPC1LMNA | |
| SCHEMBL1335946 | 0.71 | ALDH1A1 (0.54) | L3MBTL1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL20605197 | 0.71 | L3MBTL1 (0.50) | L3MBTL1ADRA2AADRA2CADRA1DADRA1A | |
| SCHEMBL28538505 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018111904-A1 | HETEROCYCLIC INHIBITORS OF MCT4 | Vettore, LLC (US) | 2018-06-21 | — | — | WO | disclosed |