Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340477 | 0.99 | LMNA (0.39) | LMNATSHRALDH1A1KMT2ANTRK1 | |
| SCHEMBL1342725 | 0.94 | NPC1 (0.39) | LMNATSHRALDH1A1KMT2ANPC1 | |
| SCHEMBL1343490 | 0.91 | L3MBTL1 (0.36) | LMNATSHRALDH1A1KMT2ANTRK1 | |
| SCHEMBL1342293 | 0.91 | NPC1 (0.36) | LMNATSHRALDH1A1KMT2ANTRK1 | |
| SCHEMBL1343660 | 0.90 | NPC1 (0.35) | LMNATSHRALDH1A1KMT2ANPC1 | |
| SCHEMBL1342386 | 0.90 | MAPT (0.42) | LMNAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL1341434 | 0.89 | ALDH1A1 (0.39) | LMNATSHRALDH1A1NTRK1NTRK2 | |
| SCHEMBL1342757 | 0.88 | LMNA (0.40) | LMNATSHRALDH1A1KMT2ANPC1 | |
| SCHEMBL1341741 | 0.88 | NPC1 (0.36) | LMNAALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL2649640 | 0.87 | MAPT (0.37) | LMNAALDH1A1KMT2ANTRK1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1531815-A1 | GLUCOKINASE ACTIVATORS | NOVO NORDISK A/S (DK) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002481-A1 | ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS | NOVO NORDISK A/S (DK) | 2004-01-08 | — | — | WO | disclosed |