SCHEMBL26512899

SCHEMBL26512899

CCC1(CC)c2ccccc2-c2c1c1c(c3cc(OC)c(OC)cc23)OC(c2ccc(OC)cc2)(c2ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)n3)cc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.36
MAPT P10636 6/20 0.36
ALDH1A1 P00352 6/20 0.36
HPGD P15428 4/20 0.36
KMT2A Q03164 4/20 0.36
HTT P42858 3/20 0.34
ACACA Q13085 2/20 0.34
LMNA P02545 1/20 0.34
LTB4R Q15722 2/20 0.32
MEN1 O00255 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
AURKA O14965 1/20 0.32
AURKB Q96GD4 1/20 0.32
MCL1 Q07820 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26512902 0.94 KDM4E (0.31) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL26512895 0.94 BRD4 (0.37) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL26512892 0.94 BRD4 (0.37) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL26512791 0.94 ACACA (0.38) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL25606273 0.94 EDNRB (0.32)
SCHEMBL25717226 0.94 EDNRB (0.32)
SCHEMBL26512894 0.92 KDM4E (0.32) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL26512886 0.92 NTSR1 (0.33) KDM4EMAPTALDH1A1KMT2AHTT
SCHEMBL26627753 0.90 PDE10A (0.32)
SCHEMBL25599862 0.90 ALDH1A1 (0.31) MAPTALDH1A1KMT2AHTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323197-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-10-12 US disclosed
US-20230323197-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-10-12 US disclosed