Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14397892 | 0.88 | ALDH1A1 (0.65) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL31432675 | 0.88 | ALDH1A1 (0.65) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5143351 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL20892596 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL4059477 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL18045690 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL12344082 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL2352641 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5654410 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL5143349 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAOBL3MBTL1CYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-0994848-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |