Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | ERN1 | O75460 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785542 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAOBERN1MAPT | |
| SCHEMBL5882846 | 0.88 | ALDH1A1 (0.65) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL20892596 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL4059477 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL18045690 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL5143351 | 0.86 | ALDH1A1 (0.67) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL12344082 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL2651293 | 0.84 | ALDH1A1 (0.65) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL426335 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAOBERN1L3MBTL1TRIM24 | |
| SCHEMBL5654410 | 0.83 | ALDH1A1 (0.63) | ALDH1A1MAOBERN1L3MBTL1TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567315-B1 | Method for synthesis of 4-OH substituted anabaseine derivative | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-02-14 | — | — | US | claimed |
| US-9567315-B1 | Method for synthesis of 4-OH substituted anabaseine derivative | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-02-14 | — | — | US | disclosed |
| US-9567315-B1 | Method for synthesis of 4-OH substituted anabaseine derivative | Institute of Nuclear Energy Research, Atomic Energy Council, Executive Yuan, R.O.C. (TW) | 2017-02-14 | — | — | US | disclosed |
| EP-2348859-B1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2013-12-04 | — | — | EP | disclosed |
| US-8354454-B2 | Prodrugs of oxazolidinone CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20110218177-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME LLC | 2011-09-08 | — | — | US | disclosed |
| EP-2348859-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010039474-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218177-A1 | PRODRUGS OF OXAZOLIDINONE CETP INHIBITORS | CETP, SLCO2B1, OXA1L | ALDH1A1 2972/4885MAOB 1069/4885ERN1 2129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.