Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26512994 | 0.94 | MAPT (0.36) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL26512649 | 0.92 | TP53 (0.32) | MAPTNPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL26513020 | 0.91 | MAPT (0.34) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL26513005 | 0.91 | BRD4 (0.41) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL26513053 | 0.91 | GPR84 (0.36) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL26513001 | 0.91 | BRD4 (0.41) | MAPTLMNACYP1A1CYP1A2CYP1B1 | |
| SCHEMBL26513018 | 0.91 | ATM (0.30) | — | |
| SCHEMBL25604650 | 0.89 | GPR84 (0.34) | MAPTLMNAGPR84NPC1RAB9A | |
| SCHEMBL25844403 | 0.89 | GPR84 (0.34) | MAPTLMNAGPR84NPC1RAB9A | |
| SCHEMBL26518759 | 0.89 | ENPP1 (0.35) | MAPTLMNACYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |