SCHEMBL25844403

SCHEMBL25844403

COc1ccc(C2(c3ccc(-c4ccc(-c5ccccc5)cc4)cc3)C=Cc3c4c(c5ccccc5c3O2)-c2ccccc2C4(C)C)cc1

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.34
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
PGR P06401 1/20 0.32
KDM4E B2RXH2 2/20 0.32
HPGD P15428 2/20 0.32
PDK2 Q15119 1/20 0.32
ACACA Q13085 1/20 0.32
MAPT P10636 2/20 0.31
LMNA P02545 2/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25604650 1.00 GPR84 (0.34) GPR84NPC1RAB9APGRKDM4E
SCHEMBL3147233 0.96 PGR (0.33) GPR84NPC1RAB9APGRKDM4E
SCHEMBL29664183 0.96 PGR (0.34) GPR84PGRKDM4EHPGDLMNA
SCHEMBL1680041 0.96 PGR (0.34) GPR84PGRKDM4EHPGDLMNA
SCHEMBL25607147 0.94 KDM4E (0.34) GPR84NPC1RAB9APGRKDM4E
SCHEMBL26512994 0.94 MAPT (0.36) GPR84NPC1RAB9AHPGDACACA
SCHEMBL25844358 0.93 LTA4H (0.35) GPR84PGRKDM4EHTTALDH1A1
SCHEMBL25604652 0.93 GPR84 (0.32) GPR84
SCHEMBL9926878 0.92 GPR84 (0.35) GPR84NPC1RAB9APGRKDM4E
SCHEMBL26513010 0.92 ACACA (0.39) GPR84KDM4EHPGDPDK2ACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4269532-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2023-11-01 EP disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-10-26 US disclosed
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 US disclosed
US-20230227717-A1 PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND SPECTACLES HOYA LENS THAILAND LTD. (TH) 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340318-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES NR2E3, CRY1, RPS10 GPR84 1058/4885NPC1 2366/4885RAB9A 1795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.