Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26513001 | 1.00 | BRD4 (0.41) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26512994 | 0.95 | MAPT (0.36) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26512634 | 0.94 | BRD4 (0.39) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26512629 | 0.94 | BRD4 (0.39) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26513007 | 0.94 | ACACA (0.36) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26513010 | 0.93 | ACACA (0.39) | BRD4ACACAMAPTHPGDLMNA | |
| SCHEMBL26513004 | 0.92 | ACACA (0.38) | BRD4ACACAMAPTADORA3HPGD | |
| SCHEMBL26513053 | 0.92 | GPR84 (0.36) | BRD4ACACAMAPTLMNACYP1A1 | |
| SCHEMBL26513016 | 0.91 | MAPT (0.33) | BRD4ACACAMAPTADORA3LMNA | |
| SCHEMBL26512580 | 0.91 | ACACA (0.36) | BRD4ACACAMAPTADORA3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |
| US-20230323197-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND SPECTACLES | HOYA LENS THAILAND LTD. (TH) | 2023-10-12 | — | — | US | disclosed |