Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2655938 | 0.88 | HDAC1 (0.46) | LSSHDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL2651773 | 0.85 | EPHX2 (0.41) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| SCHEMBL2652198 | 0.82 | LSS (0.38) | LSSHDAC1EPHX2NR1H4HDAC6 | |
| SCHEMBL2651609 | 0.77 | PLA2G2A (0.44) | HDAC1HDAC3EPHX2NR1H4HDAC6 | |
| SCHEMBL2655940 | 0.75 | PLA2G2A (0.42) | HDAC1HDAC3EPHX2NR1H4HDAC6 | |
| SCHEMBL2644845 | 0.74 | CA1 (0.53) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| SCHEMBL2484830 | 0.74 | HDAC1 (0.49) | HDAC1HDAC3HDAC2NCOR2HDAC6 | |
| Hydrochloric Acid SCHEMBL2644250 | 0.73 | CA1 (0.52) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| SCHEMBL28575351 | 0.73 | CACNA1H (0.46) | EPHX2CACNA1BCACNA1CL3MBTL1HTT | |
| SCHEMBL25042862 | 0.71 | HDAC1 (0.52) | HDAC1HDAC3HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | LSS 2509/4885HDAC1 2196/4885HDAC3 1032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.