Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651344 | 0.88 | LSS (0.39) | HDAC1HDAC3HDAC2NCOR2EPHX2 | |
| SCHEMBL2651773 | 0.83 | EPHX2 (0.41) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| SCHEMBL2655940 | 0.76 | PLA2G2A (0.42) | HDAC1HDAC3EPHX2NR1H4HDAC6 | |
| SCHEMBL2656900 | 0.76 | HDAC1 (0.50) | HDAC1HDAC3HDAC2NCOR2EPHX2 | |
| SCHEMBL2651609 | 0.76 | PLA2G2A (0.44) | HDAC1HDAC3EPHX2NR1H4HDAC6 | |
| SCHEMBL2655927 | 0.75 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2EPHX2 | |
| SCHEMBL2652198 | 0.74 | LSS (0.38) | HDAC1EPHX2NR1H4HDAC6PLA2G2A | |
| SCHEMBL2644845 | 0.73 | CA1 (0.53) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| Hydrochloric Acid SCHEMBL2644250 | 0.72 | CA1 (0.52) | HDAC3EPHX2NR1H4HDAC6MEN1 | |
| SCHEMBL2655936 | 0.72 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | NOVO NORDISK A/S (DK) | 2003-10-30 | — | — | US | disclosed |
| WO-2002040445-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203946-A1 | Glucagon antagonists/inverse agonists | GLP1R, GPR119, GCGR | HDAC1 2196/4885HDAC3 1032/4885HDAC2 2516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.