SCHEMBL26514130

SCHEMBL26514130

CC(C)(C)c1cc(Cl)cc(-n2ccc3ccccc32)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.55
KCNH2 Q12809 1/20 0.43
ROCK2 O75116 1/20 0.40
PIM1 P11309 1/20 0.40
PIM3 Q86V86 1/20 0.40
PRKD3 O94806 1/20 0.40
PRKCG P05129 1/20 0.40
PRKCB P05771 1/20 0.40
PRKCA P17252 1/20 0.40
PRKACA P17612 1/20 0.40
PRKACG P22612 1/20 0.40
PRKACB P22694 1/20 0.40
PRKCH P24723 1/20 0.40
PRKCI P41743 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCZ Q05513 1/20 0.40
PRKCD Q05655 1/20 0.40
PRKD1 Q15139 1/20 0.40
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4692987 0.84 BIRC5 (0.70) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL2196019 0.78 BIRC5 (0.61) BIRC5KCNH2PRKD3PRKCGPRKCB
SCHEMBL31310577 0.78 BIRC5 (0.61) BIRC5KCNH2PRKD3PRKCGPRKCB
SCHEMBL10153905 0.75 BIRC5 (0.64) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL29896808 0.74 BIRC5 (0.66) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL5663553 0.74 BIRC5 (0.66) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL26514128 0.73 RORC (0.36) KCNH2MGLLMAPK14HPGDALDH1A1
SCHEMBL1617973 0.73 BIRC5 (0.54) BIRC5KCNH2PRKD3PRKCGPRKCB
SCHEMBL5661839 0.72 BIRC5 (1.00) BIRC5ROCK2PIM1PIM3PRKD3
SCHEMBL29896937 0.72 BIRC5 (1.00) BIRC5ROCK2PIM1PIM3PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME SFC CO., LTD. (KR) 2023-10-12 US disclosed
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME SFC CO., LTD. (KR) 2023-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230329109-A1 POLYCYCLIC AROMATIC DERIVATIVE COMPOUND AND ORGANOELECTROLUMINESCENT DEVICE USING SAME DDT, UROD, DDC BIRC5 1451/4885KCNH2 1304/4885ROCK2 4452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.