Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.35 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20171863 | 0.71 | IGLV6-57 (0.40) | HIF1A | |
| SCHEMBL14981814 | 0.71 | TAAR1 (0.44) | — | |
| SCHEMBL26805113 | 0.70 | TAAR1 (0.38) | — | |
| SCHEMBL3049598 | 0.69 | NPSR1 (0.38) | LMNAMAPT | |
| SCHEMBL14402810 | 0.68 | THRB (0.41) | THRBMAPTHIF1ATHRA | |
| SCHEMBL13968315 | 0.68 | THRB (0.50) | THRBTHRA | |
| SCHEMBL172562 | 0.68 | THRB (0.50) | THRBTHRA | |
| SCHEMBL13878905 | 0.67 | TAAR1 (0.41) | LMNAMAPT | |
| SCHEMBL15325843 | 0.66 | F2RL1 (0.41) | LMNAMAPTXBP1HIF1A | |
| SCHEMBL24071971 | 0.65 | TP53 (0.39) | THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023194310-A1 | THERAPEUTIC COMBINATION OF KRAS G12C INHIBITOR AND TEAD INHIBITOR | SANOFI (FR) | 2023-10-12 | — | — | WO | disclosed |