SCHEMBL26522604

SCHEMBL26522604

Clc1ccccc1-c1ccc2c(c1)n1c3ccccc3c3ccc4c5ccccc5n2c4c31

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAK1 Q13153 2/20 0.39
TNKS2 Q9H2K2 1/20 0.39
HPGD P15428 2/20 0.38
TRPA1 O75762 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP2A6 P11509 1/20 0.38
JAK2 O60674 1/20 0.38
JAK1 P23458 1/20 0.38
TYK2 P29597 1/20 0.38
JAK3 P52333 1/20 0.38
ALOX5AP P20292 1/20 0.36
FEN1 P39748 1/20 0.36
TSPO P30536 1/20 0.36
BACE1 P56817 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26522758 0.94 HPGD (0.37) PAK1TNKS2HPGDTRPA1KDM4E
SCHEMBL26522745 0.94 CYP2A6 (0.40) PAK1TNKS2HPGDTRPA1KDM4E
SCHEMBL26522757 0.85 MAOA (0.39) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL26522500 0.82 DNM1 (0.41) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL26522605 0.82 DNM1 (0.41) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL15434835 0.80 RXRA (0.41) HPGDKDM4EMEN1ALDH1A1MAPT
SCHEMBL26522753 0.78 MAOA (0.43) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL26522746 0.78 DNM1 (0.41) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL26522612 0.78 MAOB (0.43) HPGDKDM4EMEN1ALDH1A1POLB
SCHEMBL26523010 0.77 HPGD (0.44) HPGDKDM4EMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023185039-A1 ORGANIC COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC APPARATUS COMPRISING SAME 陕西莱特光电材料股份有限公司 2023-10-05 WO disclosed