Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26383119 | 0.86 | POLB (0.52) | KMT2APOLBSMN1; SMN2PKMHTT | |
| SCHEMBL26522945 | 0.81 | KMT2A (0.50) | KMT2APOLBSMN1; SMN2PKMHTT | |
| SCHEMBL26522756 | 0.80 | POLB (0.49) | KMT2APOLBSMN1; SMN2PKMHTT | |
| SCHEMBL26522610 | 0.74 | POLB (0.44) | KMT2APOLBSMN1; SMN2PKMHTT | |
| SCHEMBL3132202 | 0.73 | ALDH1A1 (0.59) | POLBSMN1; SMN2HTTNPC1HPGD | |
| SCHEMBL14590551 | 0.72 | POLB (0.68) | KMT2APOLBSMN1; SMN2PKMHTT | |
| SCHEMBL1893045 | 0.71 | PYCR1 (0.52) | KMT2ASMN1; SMN2HTTNPC1HPGD | |
| SCHEMBL13838902 | 0.71 | POLB (0.47) | KMT2APOLBSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL3132249 | 0.71 | SMN1; SMN2 (0.54) | POLBSMN1; SMN2AGTR2NPC1HPGD | |
| SCHEMBL13838906 | 0.70 | POLB (0.46) | POLBSMN1; SMN2PKMHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192506-A1 | MALT1 MODULATORS AND USES THEREOF | RARIFIED BIOSCIENCES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |