Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26522756 | 0.95 | POLB (0.49) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL19750331 | 0.84 | MEN1 (0.64) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL26522610 | 0.83 | POLB (0.44) | KMT2APOLBPKMHTTSMN1; SMN2 | |
| SCHEMBL26383119 | 0.82 | POLB (0.52) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL26522653 | 0.81 | KMT2A (0.45) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL24636855 | 0.80 | POLB (0.66) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL26523045 | 0.78 | KMT2A (0.40) | KMT2AMEN1KDM4EALDH1A1SIGMAR1 | |
| SCHEMBL5790489 | 0.76 | POLB (0.69) | KMT2AMEN1POLBPKMHTT | |
| SCHEMBL18843965 | 0.75 | MEN1 (0.43) | KMT2AMEN1POLBHTTSMN1; SMN2 | |
| SCHEMBL23117635 | 0.75 | PYCR1 (0.54) | KMT2AMEN1POLBPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192506-A1 | MALT1 MODULATORS AND USES THEREOF | RARIFIED BIOSCIENCES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |