Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582088 | 0.94 | DRD2 (0.41) | CYP2D6KMT2ADRD2DRD4DRD3 | |
| SCHEMBL21821600 | 0.94 | DRD2 (0.41) | CYP2D6KMT2ADRD2DRD4DRD3 | |
| SCHEMBL26522970 | 0.89 | ALDH1A1 (0.36) | KMT2ATP53HRH3MAP1LC3BHTR7 | |
| SCHEMBL21821593 | 0.83 | DRD2 (0.38) | KMT2ADRD2DRD4DRD3TP53 | |
| SCHEMBL21821981 | 0.82 | LMNA (0.38) | CYP2D6KMT2ADRD2TP53HRH3 | |
| SCHEMBL21821591 | 0.80 | SLC18A3 (0.50) | KMT2AMAP1LC3BTSHR | |
| SCHEMBL21821965 | 0.80 | ALDH1A1 (0.39) | KMT2ATP53HRH3MAP1LC3BMAPT | |
| SCHEMBL21821639 | 0.79 | HRH3 (0.42) | DRD3HRH3 | |
| SCHEMBL21821781 | 0.75 | ALDH1A1 (0.38) | KMT2AHTTMAP1LC3BMAPT | |
| SCHEMBL29581641 | 0.75 | NR4A2 (0.34) | DRD2DRD3KDM4EMAP1LC3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632903-B1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | WIGEN BIOMEDICINE TECH SHANGHAI CO LTD (CN) | 2023-10-11 | — | — | EP | disclosed |