Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | PRF1 | P14222 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141977 | 0.80 | AKR1B1 (0.56) | MAPTPRF1RAB9AALDH1A1NPC1 | |
| SCHEMBL6536547 | 0.78 | SRD5A1 (0.50) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL23059138 | 0.76 | MAPK14 (0.47) | MAPTPRF1CA12CA1CA2 | |
| SCHEMBL11250033 | 0.76 | MAPT (0.69) | MAPTPRF1CA12CA1CA2 | |
| SCHEMBL10429668 | 0.76 | SRD5A1 (0.61) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL205164 | 0.75 | ROCK2 (0.52) | ROCK2ALDH1A1MAPK1TSHRL3MBTL1 | |
| SCHEMBL8881014 | 0.73 | TBXA2R (0.44) | MAPTPRF1RAB9AALDH1A1NPC1 | |
| SCHEMBL8137792 | 0.73 | TBXA2R (0.44) | MAPTPRF1RAB9AALDH1A1NPC1 | |
| SCHEMBL30838849 | 0.73 | RAB9A (0.45) | MAPTRAB9AALDH1A1ESR1ESR2 | |
| SCHEMBL3039890 | 0.73 | PRF1 (0.70) | MAPTPRF1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257588-A1 | SMALL MOLECULE INHIBITOR OF CATHEPSIN C AND MEDICINAL USE THEREOF | Reistone Biopharma Company Limited (CN) | 2023-10-11 | — | — | EP | disclosed |