SCHEMBL265233

SCHEMBL265233

CC1CC(=O)NN1c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
G6PD P11413 2/20 0.47
GAA P10253 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALOX5 P09917 6/20 0.46
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.38
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133351 0.82 ALOX5 (0.52) GAAALOX5ALDH1A1MAPTHPGD
SCHEMBL10373241 0.80 KMT2A (0.49) GAAALDH1A1POLBMAPT
SCHEMBL17676663 0.79 MAPT (0.52) ALOX5SMN1; SMN2DDB1CRBNUSP2
SCHEMBL27115640 0.78 ALOX5 (0.42) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL5675773 0.78 ALOX5 (0.42) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL28192987 0.77 ALOX5 (0.44) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL7530946 0.77 ALOX5 (0.44) G6PDGAAL3MBTL1ALOX5ALOX15
SCHEMBL10373538 0.77 SIRT6 (0.43) SMN1; SMN2CRBNALDH1A1MAPT
SCHEMBL21789880 0.76 LMNA (0.53) GAAALOX5ALDH1A1MAPT
SCHEMBL11111594 0.75 ALOX5 (0.40) G6PDGAAL3MBTL1ALOX5ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 806 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962201-A ASCORBIC ACID OR DERIVATIVE IN COMBINATION WITH A 3-PYRAZOLIDONE COMPOUND OR AN AMINOPHENOL COMPOUND, AND A CARBONATE SALT; CONTAINS SUBSTANTIALLY NO DIHYDROXYBENZENE COMPOUND KONICA CORPORATION (JP) 1999-10-05 US claimed
US-5766832-A CONTAINING CYCLODEXTRIN COMPOUND, ASCORBIC ACID DERIVATIVE DEVELOPER, 3-PYRAZOLIDONE OR PARA-AMINOPHENOL COMPOUND; STABILITY KONICA CORPORATION (JP) 1998-06-16 US claimed
EP-0724193-B1 Radiographic film developers containing ascorbic acid and thioether development accelerators EASTMAN KODAK CO (US) 1998-04-15 EP claimed
EP-0461783-B1 Photographic developer composition KNAPP AUDENRIED W (US) 1996-12-04 EP claimed
EP-0724193-A2 Radiographic film developers containing ascorbic acid and thioether development accelerators EASTMAN KODAK COMPANY (US) 1996-07-31 EP claimed
US-5474879-A Hydroquinone-free EASTMAN KODAK COMPANY (US) 1995-12-12 US claimed
EP-0666501-A2 Hardening developer for silver halide photography and development method EASTMAN KODAK COMPANY (US) 1995-08-09 EP claimed
US-5389502-A Black and white photography; hydroquinone and auxiliary developers, dialdehyde hardeners, antifoggants, sulfites, oligomeric carboxyl sequestering agents EASTMAN KODAK COMPANY (US) 1995-02-14 US claimed
EP-0508691-B1 Gluconic-acid based developer composition KNAPP AUDENRIED W (US) 1994-01-12 EP claimed
US-5187050-A Adding single replenisher containaing 3-pyrazolidone developer FUJI PHOTO FILM CO., LTD. (JP) 1993-02-16 US claimed
EP-0253585-B1 SILVER HALIDE LIGHT-SENSITIVE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1992-09-09 EP claimed
EP-0461783-A1 Photographic developer composition Knapp, Audenried W. (US) 1991-12-18 EP claimed
EP-0143424-B1 HEAT-DEVELOPABLE LIGHT-SENSITIVE MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1990-06-27 EP claimed
US-4863830-A Process for hard tone development of silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-09-05 US claimed
EP-0253585-A2 Silver halide light-sensitive photographic material KONICA CORPORATION (JP) 1988-01-20 EP claimed
US-4617258-A WATER SOLUBLE GROUP 8 COMPOUNDS KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1986-10-14 US claimed
US-4603103-A THERMALLY DECOMPOSABLE ORGANIC SILVER SALT ON A SUPPORT FUJI PHOTO FILM CO., LTD. (JP) 1986-07-29 US claimed
EP-0143424-A2 Heat-developable light-sensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1985-06-05 EP claimed
EP-0091788-A2 Silver halide photographic material KONICA CORPORATION (JP) 1983-10-19 EP claimed
US-3993490-A Direct positive photographic elements containing developers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-23 US claimed