Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | HTT | P42858 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23749976 | 0.81 | PARP1 (0.61) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL8623849 | 0.74 | ALDH1A1 (0.65) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL15203577 | 0.71 | TRPM5 (0.53) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL31504944 | 0.68 | ACKR3 (0.53) | ALDH1A1NPSR1TSHRALOX15KDM4E | |
| SCHEMBL29522633 | 0.68 | TSHR (0.67) | ALDH1A1SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL711283 | 0.68 | TSHR (0.67) | ALDH1A1SMN1; SMN2MAPTTSHRMAPK1 | |
| SCHEMBL26521632 | 0.67 | PARP1 (0.54) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL23657663 | 0.67 | HDAC6 (0.56) | ALDH1A1LMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL30253474 | 0.67 | SMN1; SMN2 (0.68) | ALDH1A1SMN1; SMN2TSHRGAAMAPK1 | |
| SCHEMBL29520673 | 0.67 | NOTUM (0.69) | ALDH1A1LMNASMN1; SMN2NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | IDUA, MAN2B1, GBA1 | ALDH1A1 796/4885LMNA 560/4885HTT 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.