Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | IKBKB | O14920 | 3/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3512492 | 0.82 | CYP2A6 (0.50) | GAAALDH1A1HPGDMEN1IKBKB | |
| SCHEMBL27529901 | 0.81 | GAA (0.54) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16689467 | 0.78 | IKBKB (0.41) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL16690782 | 0.78 | APP (0.50) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL1843875 | 0.74 | IKBKB (0.49) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5491089 | 0.74 | ALDH1A1 (0.58) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14234140 | 0.72 | RAB9A (0.50) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10714700 | 0.71 | ALDH1A1 (0.36) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28229746 | 0.71 | GAA (0.55) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL3301918 | 0.70 | ADORA1 (0.46) | ALDH1A1HPGDMEN1KMT2AGRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | claimed |
| US-20220356164-A1 | 2-AMINOSELENOPHEN COMPOUNDS WITH ANTI-DRUG RESISTANT BACTERIA ACTIVITY AND A METHOD OF PREPARING THE SAME | ZHUHAI JINAN SELENIUM SOURCE NANOTECHNOLOGY CO., LTD. (CN) | 2022-11-10 | — | — | US | disclosed |
| US-9278958-B2 | Anti-cancer compounds | KATHOLIEKE UNIVERSITEIT LEUVEN K.U. LEUVEN R&D (BE) | 2016-03-08 | — | — | US | disclosed |
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | UNIVERSITA DEGLI STUDI DI FERRARA (IT) | 2015-05-07 | — | — | US | disclosed |
| EP-1807411-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2007-07-18 | — | — | EP | disclosed |
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-04 | — | — | US | disclosed |
| WO-2006042850-A1 | CYANOTHIOPHENES, THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-04-27 | — | — | WO | disclosed |
| US-4692461-A | PLANT PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-08 | — | — | US | disclosed |
| EP-0224140-A1 | Thienyl urea derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4111956-A | Process for the manufacture of heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094764-A1 | Cyanothiophenes, their preparation and their use in pharmaceutical compositions | GLRB, GPR6, GRM3 | GAA 1420/4885ALDH1A1 3592/4885HPGD 3417/4885 |
| US-20220356164-A1 | 2-AMINOSELENOPHEN COMPOUNDS WITH ANTI-DRUG RESISTANT BACTERIA ACTIVITY AND A METHOD OF PREPARING THE SAME | SLC11A2, LSS, AASDHPPT | GAA 2401/4885ALDH1A1 2155/4885HPGD 1954/4885 |
| US-20150126559-A1 | NOVEL ANTI-CANCER COMPOUNDS | ATP5F1A, TP53, ABCF1 | GAA 1316/4885ALDH1A1 266/4885HPGD 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.