Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26529976 | 0.86 | KMT2A (0.42) | KDM4EKMT2AALDH1A1ALDH1A3ATAD2 | |
| SCHEMBL23723707 | 0.81 | TNKS (0.42) | KDM4EMEN1KMT2ANLRP3ALDH1A1 | |
| SCHEMBL30132053 | 0.81 | TNKS (0.42) | KDM4EMEN1KMT2ANLRP3ALDH1A1 | |
| SCHEMBL23749881 | 0.67 | TNKS (0.47) | KMT2AALDH1A1HPGD | |
| SCHEMBL30132060 | 0.66 | KMT2A (0.60) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL23723704 | 0.65 | KMT2A (0.42) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL24120936 | 0.63 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL21271734 | 0.63 | ALDH1A1 (0.62) | ALDH1A1ALDH1A3ALDH1A2 | |
| SCHEMBL26096345 | 0.62 | KMT2A (0.47) | GAAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL26097137 | 0.62 | KMT2A (0.47) | KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | GAIN THERAPEUTICS SA (CH) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140216-A1 | COMBINATION THERAPY FOR TREATING MPS1 | IDUA, MAN2B1, GBA1 | GAA 4/4885KDM4E 3566/4885MEN1 1434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.