Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26096345 | 0.88 | KMT2A (0.47) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL26097137 | 0.88 | KMT2A (0.47) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL30132053 | 0.82 | TNKS (0.42) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL23723707 | 0.82 | TNKS (0.42) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL23723624 | 0.81 | SPR (0.49) | KMT2AALPLALPIALDH1A1LMNA | |
| SCHEMBL23749976 | 0.81 | PARP1 (0.61) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL23749827 | 0.78 | KMT2A (0.65) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL30120622 | 0.78 | KMT2A (0.65) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL23723685 | 0.77 | PDE5A (0.41) | KMT2AALPLALPIALDH1A1MEN1 | |
| SCHEMBL4602302 | 0.76 | ALDH1A1 (0.69) | KMT2AALPLALPIALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |