Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 4/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE9A | O76083 | 4/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23723707 | 1.00 | TNKS (0.42) | TNKSTNKS2KMT2AALPLALPI | |
| SCHEMBL23749881 | 0.87 | TNKS (0.47) | TNKSTNKS2KMT2AALPLALPI | |
| SCHEMBL23723704 | 0.85 | KMT2A (0.42) | TNKSTNKS2KMT2AALPLALPI | |
| SCHEMBL26521975 | 0.84 | MAPT (0.46) | ALDH1A1AKT1KDM4EPOLBL3MBTL1 | |
| SCHEMBL30132060 | 0.82 | KMT2A (0.60) | TNKS2KMT2AALPLALPIALDH1A1 | |
| SCHEMBL26527738 | 0.81 | GAA (0.39) | KMT2AALDH1A1KDM4EMEN1NLRP3 | |
| SCHEMBL23723853 | 0.81 | TNKS (0.40) | TNKSTNKS2KMT2AALPLALPI | |
| SCHEMBL23723639 | 0.80 | ALDH1A1 (0.52) | KMT2AALPLALPIALDH1A1LMNA | |
| SCHEMBL30368715 | 0.79 | KMT2A (0.45) | TNKSTNKS2KMT2AALPLALPI | |
| SCHEMBL23723509 | 0.78 | KMT2A (0.41) | TNKSTNKS2KMT2AALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100015-A1 | COMBINATION THERAPY FOR TREATING MPS1 | Gain Therapeutics SA (CH) | 2022-12-14 | — | — | EP | disclosed |