SCHEMBL26528341

SCHEMBL26528341

COC(=O)CCN1CCN(CCO)CC1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.57
TP53 P04637 5/20 0.51
TSHR P16473 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4489670 0.92 SMN1; SMN2 (0.65) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL1174392 0.92
SCHEMBL31442406 0.89 TSHR (0.50) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL1725970 0.88 SMN1; SMN2 (0.61) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL31317354 0.84 ALDH1A1 (0.45) SMN1; SMN2TP53L3MBTL1ALDH1A1KDM4E
SCHEMBL28996592 0.84 SMN1; SMN2 (0.57) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL5483874 0.83 SMN1; SMN2 (0.61) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL65886 0.83 SMN1; SMN2 (0.61) SMN1; SMN2TSHRL3MBTL1ALDH1A1KDM4E
SCHEMBL22878472 0.82 SMN1; SMN2 (0.56) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1
SCHEMBL31292119 0.82 SMN1; SMN2 (0.60) SMN1; SMN2TP53TSHRL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023183616-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2023-09-28 WO disclosed