SCHEMBL65886

SCHEMBL65886

COC(=O)CCN1CCCC1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.61
ALDH1A1 P00352 5/20 0.54
MAPT P10636 4/20 0.54
POLB P06746 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 3/20 0.51
ALOX15 P16050 1/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
GLA P06280 1/20 0.45
ATM Q13315 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP1A2 P05177 1/20 0.45
MAPK1 P28482 1/20 0.45
FPR3 P25089 1/20 0.44
FPR2 P25090 1/20 0.44
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL4607935 0.98 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
SCHEMBL10409891 0.98 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
SCHEMBL65134 0.98 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
Hydrochloric Acid SCHEMBL9409653 0.96 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
SCHEMBL5483874 0.96 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
SCHEMBL1174392 0.91
SCHEMBL4489670 0.91 SMN1; SMN2 (0.65) SMN1; SMN2ALDH1A1MAPTL3MBTL1TSHR
SCHEMBL1856574 0.88 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1
SCHEMBL1725970 0.87 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1MAPTL3MBTL1TSHR
SCHEMBL12014428 0.87 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1MAPTPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN claimed
US-4267362-A Process for the preparation of delta keto-acids and derivatives thereof STAMICARBON, B.V. (NL) 1981-05-12 US claimed
EP-4660703-A2 METAL-CONTAINING FILM PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2025-12-10 EP disclosed
CN-119823068-A Preparation method of cephalosporin antibacterial key intermediate 上海再启生物技术有限公司 2025-04-15 CN disclosed
US-12032287-B2 Resist material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-09 US disclosed
US-11994798-B2 Resist material and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-05-28 US disclosed
WO-2024102434-A1 RNA COMPOSITIONS COMPRISING LIPID NANOPARTICLES OR LIPID RECONSTRUCTED NATURAL MESSENGER PACKS SENDA BIOSCIENCES, INC. (US) 2024-05-16 WO disclosed
WO-2023207102-A1 LIPID NANOPARTICLES Beijing Jitai Pharmaceutical Technology Co., Ltd. (CN) 2023-11-02 WO disclosed
WO-2023183616-A1 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2023-09-28 WO disclosed
CN-114394898-A Preparation method of 5-oxohexanoate 山东智永化工产业技术研究院有限公司 2022-04-26 CN disclosed
US-11274102-B2 Compounds useful in HIV therapy GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2022-03-15 US disclosed
EP-1195390-A1 Polymer, resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-04-10 EP disclosed
US-5476934-A Oxidation a nitrogen-containing perfluoroacyl halide AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1995-12-19 US disclosed
US-5380844-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY, MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1995-01-10 US disclosed
US-5347002-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1994-09-13 US disclosed
US-5256825-A Promoter for fluoropolymer, heat exchanging AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1993-10-26 US disclosed
US-5208339-A Nitrogen-containing perfluoroalkanoyl peroxide and method for production thereof AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1993-05-04 US disclosed
EP-0008482-B1 PROCESS FOR THE PREPARATION OF DELTA KETO-ACIDS AND DERIVATIVES THEREOF STAMICARBON B.V. (NL) 1983-04-20 EP disclosed
US-4267362-A Process for the preparation of delta keto-acids and derivatives thereof STAMICARBON, B.V. (NL) 1981-05-12 US disclosed
EP-0008482-A1 Process for the preparation of delta keto-acids and derivatives thereof STAMICARBON B.V. (NL) 1980-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11274102-B2 Compounds useful in HIV therapy CCR5, CD4, G6PD SMN1; SMN2 3016/4885ALDH1A1 684/4885MAPT 589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.